Critical Care Observation of Motor Activity (COMA) and SICU Outcomes

Mass General Brigham

Status: Completed

Conditions: Muscle Strength; Muscle Weakness; Motor Activity

Treatments: Procedure: COMA Score Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT02994641

2015P002568

Details and patient eligibility

About

In the surgical intensive care unit (SICU), goals of critical care are often discussed in long-term ventilated patients around the time of extubation. Muscle weakness predicts extubation failure but formal muscle strength assessment by the Medical Research Council scale is time-consuming and not part of the daily clinical exam. In this observational study, we hypothesize that COMA measurement, routinely used by the SICU nurses, is a reliable and valid predictor for patients' SICU outcomes. This prospective observational study is carried out within a consecutively enrolled cohort of adult patients who are extubated in two SICUs at Massachusetts General Hospital, Boston.

Enrollment: 761 patients

Sex: All

Ages: 18 to 112 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Intubated and mechanically ventilated patients in 2 ICUs at Massachusetts General Hospital
• adult patients

Exclusion criteria

• Tracheostomy without extubation attempt
• Death without extubation attempt/terminal extubation

Trial design

761 participants in 2 patient groups

Adverse discharge disposition

Description:

Patients who were discharged to a skilled nursing facility or died in the hospital

Treatment:

Procedure: COMA Score Assessment

No adverse discharge disposition

Description:

Patients who were not discharged to a skilled nursing facility or did not die in the hospital

Treatment:

Procedure: COMA Score Assessment