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"Critical State" Early Warning Score After CHD Surgery and Rapid Response Team

C

Chinese Academy of Medical Sciences, Fuwai Hospital

Status

Completed

Conditions

Congenital Heart Disease

Study type

Observational

Funder types

Other

Identifiers

NCT06578312
2022-GSP-GG-32

Details and patient eligibility

About

By establishing a warning scoring tool for the early "critical state" after congenital heart disease surgery, the multidisciplinary rapid response team is proactively activated, forming an integrated treatment model of early warning-team decision-making-organ assistance.

Full description

All children aged 0-14 years admitted to the PICU from 2021-2022 were enrolled continuously, and their baseline data such as gender, age, RACHS-1 score, cardiopulmonary bypass time, aortic clamping time, whether there was chromosomal lesions, whether there was preoperative endotracheal intubation/heart failure, changes in oxygenation index, lactate, and vasoactive drug scores were obtained. All variables that may lead to composite malignant events including death in the early postoperative period were included, including death, pulmonary hypertension crisis, malignant arrhythmias (supraventricular tachycardia, ventricular tachycardia, ventricular fibrillation, high-degree atrioventricular block) requiring antiarrhythmic drugs or pacemaker treatment, cardiopulmonary resuscitation, ECPR, emergency sternal expansion, severe AKI, severe ARDS, neurological complications (cerebral hemorrhage, cerebral infarction), gastrointestinal complications (gastrointestinal bleeding, intestinal obstruction, intestinal necrosis).The variables were included in the machine learning analysis to establish the model.

Enrollment

4,115 patients

Sex

All

Ages

28 days to 14 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • pediatrics admitted to ICU

Exclusion criteria

  • surgery without cardiopulmonary bypass
  • neonatal
  • using extra-corporeal circulation during surgery
  • Delayed chest closing during surgery

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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