Cross Linking for Treatment of Corneal Infection

Price Vision Group

Status: Terminated

Conditions: Infectious Keratitis

Treatments: Device: UVX Light; Drug: riboflavin

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00912509

2008-0143

Details and patient eligibility

About

This study is comparing 45 minute and 30 minute treatment durations with the UVX corneal cross linking system to treat corneal infections.

Enrollment: 30 patients

Sex: All

Ages: 14+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of infectious keratitis

Exclusion criteria

• corneal ulcer that has perforated
• corneal ulcer that has produced a descemetocele
• women who are pregnant or breastfeeding
• patients who are immunocompromised or unwilling or unable to comply with a medication regimen

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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30 participants in 2 patient groups

30 minute light duration

Active Comparator group

Description:

30 minute treatment with UVX light

Treatment:

Drug: riboflavin

Device: UVX Light

45 minute light duration

Active Comparator group

Description:

45 minute treatment with UVX light

Treatment:

Device: UVX Light