Cross-sectional Study of Prevalence Rate of Abdominal Aortic Aneurysm in OSAHS Patients From BTCH

Beijing Tsinghua Chang Gung Hospital

Status: Unknown

Conditions: Sleep Apnea, Obstructive; AAA - Abdominal Aortic Aneurysm

Study type: Observational

Funder types: Other

Identifiers

NCT03431038

17084-0310

Details and patient eligibility

About

This study explore AAA prevalence in OSAHS patients by ultrasound screening and try to analysis risk factors of AAA in OSAHS patients.

Full description

Abdominal aortic aneurysm (AAA) is an extremely high mortality disease, and ultrasound has been recommended for the screening of AAA, which is highly sensitive and specific. Studies have shown that screening for AAA in the population can significantly reduce deaths from ruptured abdominal aortic aneurysms. However, those study mainly focus on cardiovascular disease patients or general population, no previous study target on obstructive sleep apnea hypopnea syndrome (OSAHS) population. Retrospective studies show that the incidence of apnea syndrome in patients with abdominal aortic aneurysm is higher than that in the control group, which suggests that OSAHS may be one of the causes of abdominal aortic aneurysm. At present, there is no relevant research on the screening of AAA in OSAHS population.

The main objective of this study was to screen the prevalence of AAA in OSAHS population by a cross-sectional study.

Enrollment: 1,800 estimated patients

Sex: All

Ages: 45+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients who accept respiratory sleep monitoring in the department of ENT, BTCH, aged over 45 years, from 2018-01-01 to 2019-12-30

Exclusion criteria

• 1. Any previous diagnosis of AAA history;
• 2. Received AAA related treatment;
• 3. Past imaging test result suggested increased diameter of the abdominal aorta.
• 4. Poor compliance; refused to follow the requirements set in this study follow-up, and refused to sign informed consent.