Cross-sectional Study of Use of Speckle Method in Early Diagnosis of Cardiovascular Dysfunction (SPEEDCARS)

University of Roma La Sapienza

Status: Unknown

Conditions: Sjogren Syndrome

Treatments: Procedure: Speckle tracking echocardiography

Study type: Observational

Funder types: Other

Identifiers

NCT02132585

Spk-001

Details and patient eligibility

About

Speckle tracking (STE) is a novel echocardiographic technique which permits calculation of myocardial velocities and deformation parameters such as strain and strain rate (SR). It is demonstrated that these parameters provide important insights into systolic and diastolic function, ischaemia, myocardial mechanics and many other pathophysiological processes of the heart. In this preliminary study, we investigated the role of STE in detection of early ventricular dysfunction in patients with Sjogren Syndrome, focusing on cardiorespiratory fitness.

Enrollment: 700 estimated patients

Sex: All

Ages: 40 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosis of Sjogren Syndrome

Exclusion criteria

• previous cardiovascular events
• unstable angina
• stroke
• diagnosis of heart failure
• incapacity to provide an informed consent

Trial design

700 participants in 2 patient groups

Sjogren

Description:

Sjogren Patients evaluated with Speckle tracking echocardiography

Treatment:

Procedure: Speckle tracking echocardiography

Control

Description:

Controls Speckle tracking echocardiography

Treatment:

Procedure: Speckle tracking echocardiography