Cryoablation Versus Radiofrequency Ablation for Small Renal Masses

St. Joseph's Healthcare Hamilton

Status and phase

Withdrawn

Phase 2

Conditions

Renal Cancers

Treatments

Procedure: Radiofrequency ablation

Procedure: Cryoablation

Study type

Interventional

Funder types

Other

Identifiers

NCT00922948

IIS-001-09

Details and patient eligibility

About

The purpose of this study is to verify the oncological efficacy and safety of cryoablation and radiofrequency ablation for the treatment of small renal tumors.

Full description

By enrolling all patients treated with CA or RFA, this study will document for the first time the safety and the short and long term efficacy of CA compared to RFA as well as provide urologists and decision makers currently unavailable information on CA in Canada.

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with tumors that progress in size while on a watchful waiting protocol;
Patients with multiple tumors;
Patients with a tumor in a solitary kidney;
Patients with poor renal function and a renal tumor;
Patients with significant co-morbidities that may benefit from a less invasive approach.

Exclusion criteria

Large tumors > 4.0cm;
Unable to have a general anesthetic;
Unable to comply with follow-up protocol (i.e., routine CT or MRI and a follow-up biopsy);
Uncorrectable bleeding diathesis;
Evidence of metastatic disease.