Cryoanalgesia for Irreversible Pulpitis (CryPain)

Universitat Internacional de Catalunya

Status: Completed

Conditions: Pulpitis - Irreversible

Treatments: Procedure: Cold Mepivacaine; Procedure: Mepivacaine at room temperature

Study type: Interventional

Funder types: Other

Identifiers

NCT06268912

END-ECL-2022-01 (Other Identifier)

Details and patient eligibility

About

The aim of the present study was to evaluate the effectiveness of pulpal anesthesia in pain control during endodontic treatment by lowering the temperature of the injected plain 3% cold Mepivacaine (5ºC) compared to 3% Mepivacaine at room temperature in teeth with irreversible pulpitis.

Full description

Mepivacaine has some advantages over other anesthetics. The investigators wanted to compare whether changing temperature could improve its effectiveness in cases of irreversible pulpitis.

Enrollment: 20 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All Patients within the age group of 18-100 years old,

• Patients diagnosed of irreversible pulpitis.

Exclusion criteria

• Moderate to pulp necrosis,
• Previous initiated treatment.
• Pregnancy or lactation.
• Allergy or problems to any substances used in the study,
• Acute apical abscess.
• Chronic apical abscess.
• Unrestorable teeth.
• Unsuccessful anesthesia technique (no lip numbness for lower molars or positive response to cold test).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20 participants in 2 patient groups

Cold Mepivacaine

Experimental group

Description:

Mepivacaine 3% at 5ºC

Treatment:

Procedure: Cold Mepivacaine

Mepivacaine at room temperature

Active Comparator group

Description:

Mepivacaine 3% at room temperature

Treatment:

Procedure: Mepivacaine at room temperature