Cryobiopsy vs. VATS in Diagnosis of Interstitial Lung Diseases

Wissenschaftliches Institut Bethanien e.V

Status: Completed

Conditions: Interstitial Lung Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01714518

WI_KryoVATS_80/2012

Details and patient eligibility

About

The purpose of this study is to assess efficiency and safety of cryobiopsy compared to video-assisted thoracoscopic lung biopsy (VATS) in diagnosis of interstitial lung diseases (ILD). To that end, this non-interventional study prospectively collects data from patients undergoing routine diagnosis of ILD. In some of those patients less invasive diagnostic approaches do not yield a definitive diagnosis. Thus, they will ultimately be subjected to VATS if this procedure is reasonable. The information gained by this study will help to assess the significance of cryobiopsy in contrast to VATS in this particular disease group.

Enrollment: 62 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Known or newly diagnosed interstitial lung disease (ILD)
• Indication for lung biopsy for definitive ILD diagnosis
• Informed Consent provided

Exclusion criteria

• Age < 18 years
• Inability or contraindication to undergo any form of invasive diagnostic procedure associated with diagnosis of interstitial lung disease
• Severely restricted CO diffusion capacity (<50%)
• Pregnancy, lactation
• Any medical, psychological or other condition restricting the patient's ability to provide informed consent
• Participation in another clinical trial

Trial design

62 participants in 1 patient group

ILD diagnosis

Description:

Patients subjected to Cryobiopsy and/or VATS for diagnosis of interstitial lung disease