Crystalloids for AKI in Shock Patients

Southeast University, China

Status: Unknown

Conditions: Shock

Treatments: Drug: Fluid resuscitation

Study type: Interventional

Funder types: Other

Identifiers

NCT03188614

2017ZDSYLL018P

Details and patient eligibility

About

Fluid resuscitation is important in shock therapy, but the choice of fluids, especially the choice of crystalloid is under debate. It is said that normal saline is related to hyperchloremia， which might lead to acute kidney injury. Thus the hypothesis of the study is to explicit whether balanced salt solution could reduce the incidence of acute kidney injury when compared with normal saline.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Shock patients

Exclusion criteria

• History of chronic renal failure

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 2 patient groups, including a placebo group

Normal saline group

Placebo Comparator group

Description:

Shock patients who resuscitated with normal saline were enrolled between June, 2015-June.2016.

Treatment:

Drug: Fluid resuscitation

Balanced solution group

Experimental group

Description:

Shock patients who resuscitated with balanced solution were enrolled after June, 2016.

Treatment:

Drug: Fluid resuscitation