CT DOSE Collaboratory

University of California San Francisco (UCSF)

Status: Completed

Conditions: Quality Improvement; Ionizing Radiation Exposure

Treatments: Other: Simple Audit Report; Other: Multi-Component Intervention; Other: In-Person Meeting

Study type: Interventional

Funder types: Other; Other U.S. Federal agency; NIH

Identifiers

NCT03000751

RSB-181191

R01CA181191 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This is a pragmatic stepped-wedge cluster randomized controlled trial to explore variation in doses used for diagnostic CT by pooling radiation dose data across diverse healthcare delivery systems.

To compare different strategies for lowering and optimizing dose and identify the barriers and facilitators to implementing successful dose optimization strategies and standardizing practice.

Full description

The investigators are using a stepped-wedge cluster randomized controlled trial, collecting radiation dose information on CT from across all collaborating health care facilities, and leading several different interventions to optimize dose across facilities. In addition to collecting the CT radiation dose data, and using these results to provide feedback to the collaborating health care facilities, they will be conducting surveys of several individuals at each site, including key informants, such as lead radiologists, technologists, and medical physicist, and radiology administrators.

They will compare and identify facilitators and barriers (assessed through surveys of participating facilities) associated with successful and failed implementation of dose optimization.

Enrollment: 864,080 patients

Sex: All

Ages: Under 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnostic CT scans of the head, chest, and/or abdomen/pelvis performed within the study period

Exclusion criteria

• non-diagnostic scans that are not of the head, chest, and/or abdomen/pelvis

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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864,080 participants in 3 patient groups

Track A

Active Comparator group

Description:

Simple Audit Report; In-Person Meeting (timed to coincide with the multi-component intervention); Multi-Component Intervention

Treatment:

Other: Simple Audit Report

Other: Multi-Component Intervention

Other: In-Person Meeting

Track B

Active Comparator group

Description:

In-Person Meeting (timed to coincide with the simple audit report); Simple Audit Report; Multi-Component Intervention

Treatment:

Other: Simple Audit Report

Other: Multi-Component Intervention

Other: In-Person Meeting

Track C

Other group

Description:

Simple Audit Report; Multi-Component Intervention

Treatment:

Other: Simple Audit Report

Other: Multi-Component Intervention