CT Imaging for Guiding PA-TACE for HCC

Zhujiang Hospital

Status: Completed

Conditions: Carcinoma, Hepatocellular

Treatments: Procedure: postoperative adjuvant transarterial chemoembolization

Study type: Observational

Funder types: Other

Identifiers

NCT06156748

2019-KY-021-01

Details and patient eligibility

About

Postoperative adjuvant transarterial chemoembolization (PA-TACE) may improve survival outcomes in a subset of patients with resected hepatocellular carcinoma (HCC), reliable biomarkers for the criterion for the selection of candidates are lacking. The present study aimed to evaluate whether CT imaging can provide more value for predicting benefit from PA-TACE.

Enrollment: 1,770 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• CT scans acquired no more than one month before surgery
• Confirmation of HCC diagnosis by pathological examination
• Curative surgical resection

Exclusion criteria

• Prior antitumor treatment
• Macrovascular thrombosis or metastasis
• Perioperative mortality
• Unqualified image artifacts
• Tumor rupture
• MVI status not reported

Trial design

1,770 participants in 2 patient groups

Hepatectomy alone

Treatment:

Procedure: postoperative adjuvant transarterial chemoembolization

PA-TACE