CT in Calcified Coronary Arteries With Photon Counting Detector (CCT-PCD-1)

Region Örebro County

Status: Terminated

Conditions: Calcific Coronary Arteriosclerosis; Coronary Stenosis

Treatments: Diagnostic Test: Cardiac CT with photon counting detector

Study type: Observational

Funder types: Other

Identifiers

NCT05551351

278326

Details and patient eligibility

About

Coronary CT angiography is challenging in patients with more than mildly calcified coronary vessels, because of calcium artefacts that prevents evaluation of the lumen. The purpose of the CCT-PCD-1-study is to evaluate the diagnostic accuracy and image quality in coronary CT angiography using a commercially available CT system equipped with a photon counting detector technology.

Patients referred for cardiac CT and conventional coronary angiography as part of routine preoperative evaluation before Transcatheter Aortic Valve Implantation (TAVI) will be asked for inclusion in the study. This group of patients has generally a coronary artery calcium burden and perform cardiac CT and coronary angiography as part of routine care.

The diagnostic accuracy concerning significant coronary artery stenosis on the preoperative CT will be evaluated with the conventional coronary angiography as reference. Also, CT examination image quality will be evaluated.

Enrollment: 29 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients referred for cardiac CT AND conventional coronary angiography as part of routine preoperative evaluation.

Exclusion criteria

• <65 years old.
• Heart arrhythmia.
• Heart rate >90/min with contraindication against beta blockers.
• Not capable of giving informed consent
• eGFR <30 mL/min/1.73m2

Trial design

29 participants in 1 patient group

Coronary CT

Description:

The single cohort consists of all patients enrolled in the study. All participants performs cardiac CT and coronary angiography as part of routine care.

Treatment:

Diagnostic Test: Cardiac CT with photon counting detector