CT in Diagnosing Patients With Lung Cancer

Virginia Commonwealth University (VCU) logo

Virginia Commonwealth University (VCU)

Status

Completed

Conditions

Lung Cancer

Treatments

Procedure: cone-beam computed tomography
Procedure: computed tomography
Procedure: 4-dimensional computed tomography

Study type

Interventional

Funder types

Other

Identifiers

NCT01888510
MCC-15032
NCI-2013-01163 (Registry Identifier)

Details and patient eligibility

About

This clinical trial studies computed tomography (CT) in diagnosing patients with lung cancer. Diagnostic procedures, such as CT, may help find and diagnose lung cancer.

Full description

PRIMARY OBJECTIVES: I. Conduct a prospective clinical imaging study to quantify the amount of inter- and intra-physician contouring variability on four dimensional (4D) CT, active breathing control (ABC) CT, free breathing CT, and free breathing and ABC cone beam (CB)CT. II. Quantify the magnitude and distribution of target and organ at risk volume variations between the different imaging modalities. III. Determine dosimetric changes related to contouring variations for tumor and normal tissue. OUTLINE: Patients undergo conventional free breathing CT, 4D CT, ABC CT, ABC CBCT, and free breathing CBCT before undergoing radiation therapy.

Enrollment

10 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Measurable disease on CT scan
  • Patients with lung cancer visible on CT who are scheduled to receive external beam radiation treatment will be eligible for this study
  • Patients must be able to perform ABC procedures

Exclusion criteria

  • Patients requiring continuous supplemental oxygen due to the requirement of spirometry during all imaging studies
  • No vulnerable populations will be enrolled (prisoners, children, pregnant females or institutionalized individuals)
  • Women of childbearing potential will undergo a pregnancy test

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

10 participants in 1 patient group

Diagnostic (imaging studies)
Experimental group
Description:
Patients undergo conventional free breathing CT, 4D CT, ABC CT, ABC CBCT, and free breathing CBCT before undergoing radiation therapy.
Treatment:
Procedure: 4-dimensional computed tomography
Procedure: computed tomography
Procedure: cone-beam computed tomography

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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