CT Scan Guide Percutaneous Biopsy of Lytic Bone Metastases of Lung Cancer : Contribution in Pathology Diagnosis and Molecular Biology (stasfa)

Grenoble Alpes University Hospital Center (CHU)

Status: Unknown

Conditions: Image-Guided Biopsy - Carcinoma, Bronchogenic / Diagnosis- Outpatients

Treatments: Procedure: CT scan guide percutaneous biopsy of lytic bone metastases of lung cancer

Study type: Observational

Funder types: Other

Identifiers

NCT03386916

38RC17.218

Details and patient eligibility

About

In case of primary lung cancer, bone metastases biopsy can be done in initial diagnosis or follow-up.

Nevertheless, any study focus on rentability and biopsy complications of lytic bone lesion for the context of lung cancer.

This study aims to demonstrate that CT scan guide percutaneous biopsy of lytic bone lesion help to anatomopathologic diagnosis and molecular biology with a low complication rate inasmuch a lung cancer is suspected.

This study is observational, retrospective, one center

Full description

Current progress in thoracic oncology require to be able to carry out analysis by molecular biology. So biopsies are done several times during cancer progression. But risk is high for a lung biopsy with enough sample, so a CT scan guide percutaneous biopsy of lytic bone metastases of lung cancer can be an alternative.

In case of primary lung cancer, bone metastases biopsy can be done in initial diagnosis or follow-up. But this contribution in diagnostic (anatomopathologic an molecular biology) is poorly understood. It is demonstrated that to sample on lytic bone lesion have a failure rate lower than on calcified osseous lesion. Nevertheless, any study focus on rentability and biopsy complications of lytic bone lesion for the context of lung cancer.

this study aims to demonstrate that CT scan guide percutaneous biopsy of lytic bone lesion help to anatomopathologic diagnosis and molecular biology with a low complication rate inasmuch a lung cancer is suspected.

This study is observational, retrospective, descriptive, one-center Patient's records selection will be done by keyword search on the CHU Grenoble Alpes radiology software. Only records with bone biopsy register between January 2010 and June 2017 will be included.

Enrollment: 80 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• CT scan guide percutaneous biopsy of lytic bone metastases
• register on CHU Grenoble Alpes radiology software between January 2010 and June 2017
• Patient who have a clinical context of lung cancer with bone metastases

Exclusion criteria

• Person deprived of liberty by judicial order
• Opposition expressed by patient

Trial design

80 participants in 1 patient group

Patient with a CT scan guide percutaneous biopsy of lytic bone

Description:

Patient with a CT scan guide percutaneous biopsy of lytic bone metastases register on CHU Grenoble Alpes radiology software between January 2010 and June 2017

Treatment:

Procedure: CT scan guide percutaneous biopsy of lytic bone metastases of lung cancer