CTC in Lung Caner Patients With Bone Metastases

Shanghai Jiao Tong University

Status: Unknown

Conditions: Single Cell Sequencing Technology; Lung Cancer; Bone Metastases

Treatments: Other: model treatment; Other: routine treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT04568291

CTC01

Details and patient eligibility

About

1. Evaluate the feasibility of single cell sequencing technology based on three-dimensional bionic capture network;
2. To build a risk prediction model of bone related events based on single cell sequencing;
3. To verify the risk prediction model of bone related events by single cell sequencing;
4. To verify the comprehensive treatment of non-small cell lung cancer ( NSCLC) bone metastases.

Enrollment: 160 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. age 18-75 years
2. pathology-proven diagnosis of lung cancer and radiographical/pathological evidence of BM
3. no previous treatment for BM
4. good general condition (Eastern Cooperative Oncology Group, ECOG Performance scores: 0-2) with an estimated survival time > 3 months.

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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160 participants in 2 patient groups

routine treatment

Active Comparator group

Description:

routine treatment

Treatment:

Other: routine treatment

model treatment

Experimental group

Description:

model treatment

Treatment:

Other: model treatment