CTCs for High Grade Glioma

Abramson Cancer Center at Penn Medicine

Status: Completed

Conditions: Stage III and IV Glioma Patients

Study type: Observational

Funder types: Other

Identifiers

NCT02558335

UPCC 09313

Details and patient eligibility

About

The purpose of this study is to identify and quantify circulating tumor markers, which are associated with the presence of tumors. The current imaging available does not allow specificity of tumor size as it relates to pseudoprogression (a temporary enlargement or "swelling" of the tumor after treatment before it shrinks). Our hope is that CTCs will provide a more accurate description of tumor state for high grade glioma patients.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Patients with biopsy-proven high grade glioma who are undergoing definitive radiotherapy as a part of their treatment regimen or patients with radiographic appearance of high grade glioma
• Age 18 or older
• Signed informed consent

Exclusion Criteria: