Culturally Adapted Psychoeducation (CaPE) for Bipolar Disorders in Nigeria

Nottingham Trent University

Status: Not yet enrolling

Conditions: Bipolar Disorder

Treatments: Behavioral: Culturally adapted Psychoeducation (CaPE); Drug: Treatment as Usual (TaU)

Study type: Interventional

Funder types: Other

Identifiers

NCT05721196

0000-0001-5034-0335e

Details and patient eligibility

About

Bipolar disorders are chronic mental health disorders that often result in functional impairment, constituting a significant disease burden. It also accounts for seven per cent of disability-adjusted life years caused by mental disorders. Four out of ten persons with a probable diagnosis of bipolar disorders received no mental health care within the preceding twelve months. Compared to the general population, individuals with bipolar disorders tend to have a significantly higher rate of associated suicide mortality. Within the last decade, these mortality rates have substantially increased, suggesting the need for targeted research to address the unresolved needs of individuals suffering from bipolar disorders. A recent meta-analysis found that compared to the general population, bipolar patients had reduced life expectancy with about thirteen years of potential life loss.

Bipolar disorders are historically under-researched compared to other mental health disorders, especially in Sub-Saharan Africa and Nigeria. Our recent study on bipolar disorders in Nigeria provided insight into contextual knowledge and beliefs about bipolar disorders, including the lived experiences of patients with bipolar disorders, their caregivers, and clinicians in Nigeria. The study recommended culturally adapted psychosocial intervention for bipolar patients, hence the proposed research.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diagnosis of DSM IV bipolar affective disorder
• currently euthymic (BDI < 12 and YMRS < 8)
• age 18-65 years, participants engaged with the mental health services for the preceding 6 months
• able to give written informed consent
• resident of the trial catchment area and
• the ability to speak English.

Exclusion criteria

• severe cognitive impairment
• currently experiencing relapse (mania, hypomania, mixed or depressive)
• being actively suicidal
• the presence of any comorbid psychiatric illness such as substance misuse or alcohol dependence according to DSM IV criteria.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups

Culturally adapted Psychoeducation (CaPE)

Experimental group

Treatment:

Behavioral: Culturally adapted Psychoeducation (CaPE)

Treatment as Usual (TaU)

Active Comparator group

Treatment:

Drug: Treatment as Usual (TaU)