Culturally Targeted Health Communication and Receptivity to the Human Papillomavirus Vaccine Among Parents in Flint, MI

Michigan State University

Status: Enrolling

Conditions: HPV Vaccination

Treatments: Behavioral: General HPV Vaccine Health Messaging; Behavioral: Culturally Targeted HPV Vaccine Health Messaging

Study type: Interventional

Funder types: Other

Identifiers

NCT07301905

00630245

Details and patient eligibility

About

The goal of this clinical trial is to learn if culturally targeted messaging about the human papillomavirus (HPV) increases receptivity to the HPV vaccine among African American parents of vaccine-eligible daughters. The main question it aims to answer is:

• Does culturally targeted messaging increase African American parents' intentions to vaccinate their daughter against HPV?

Research will compare culturally targeted messaging to general, educational messaging and no messaging.

Participants will:

• View culturally targeted messages, education-only messages, or no messages about the HPV vaccine
• Report their intentions to vaccinate their daughter against HPV
• Report whether they have initiated HPV vaccination for their daughter six months later

Full description

Cervical cancer incidence and mortality are higher for African American women than for White women. The human papillomavirus (HPV) vaccine is the most effective strategy for reducing risk for cervical cancer. However, African American girls are less likely to have completed the HPV vaccine series than White girls. The present research will evaluate a culturally targeted approach to health messaging about the HPV vaccine for parents with vaccine-eligible daughters. The central hypothesis is that African American parents will have greater receptivity to the HPV vaccine after receiving culturally targeted messaging compared to parents who receive no messaging or education-only messaging about HPV vaccination. The primary aims are: 1) evaluate effects of HPV vaccine education on White and African American parents' receptivity to the HPV vaccine, and whether culturally targeted messaging enhances HPV vaccine receptivity among African American parents, 2) compare effects of education-only versus culturally targeted messaging on activation of racism-related thinking when considering child HPV vaccination, and 3) examine the effects of racism-related medical mistrust on the effectiveness of culturally targeted messaging. General and culturally targeted messaging about the HPV vaccine were developed in collaboration with community members and a local health educator. Participants will report their intentions to vaccinate their daughter against HPV immediately after viewing health messaging, as well as initiation of the HPV vaccine series for their daughter 6-months post-messaging.

Enrollment: 265 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Identify as Black/African American or White/Caucasian
• Have at least one daughter who is between 8-17 years of age, who is not currently pregnant, and who has not received any doses of the HPV vaccine

Exclusion criteria

• N/A

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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265 participants in 5 patient groups

African American Culturally Targeted Messaging

Experimental group

Description:

Culturally targeted messaging about the HPV vaccine for African American parents

Treatment:

Behavioral: Culturally Targeted HPV Vaccine Health Messaging

African American General, Education-Only Messaging

Active Comparator group

Description:

African American participants receive general, education-only messaging about the HPV vaccine.

Treatment:

Behavioral: General HPV Vaccine Health Messaging

African American No Message

No Intervention group

Description:

African American participants receive no messaging about the HPV vaccine

White General, Education-Only Messaging

Active Comparator group

Description:

White participants receive general, education-only messaging about the HPV vaccine.

Treatment:

Behavioral: General HPV Vaccine Health Messaging

White No Message

No Intervention group

Description:

White participants receive no messaging about the HPV vaccine