Customization of Cardiac Readaptation Based on Force-velocity Profile and Heart Rate Variability (PROPIU)

Centre Hospitalier Universitaire de Saint Etienne

Status: Enrolling

Conditions: Acute Coronary Syndrome

Treatments: Other: training strategy with adaptation of training strategies to the ANS; Other: training strategy (standard practice)

Study type: Interventional

Funder types: Other

Identifiers

NCT06107452

2023-A01452-43 (Other Identifier)

23CH152

Details and patient eligibility

About

Cardiac readaptation aims to mitigate cardiovascular risks and enhance the quality of life among coronary patients. Our research laboratory has an international expertise in training optimization in top-athletes and a previous study has demonstrated the efficacy of optimizing cardiac rehabilitation through the power-force-velocity profile (PFVP). The findings exhibited significant improvements in aerobic capacity, muscular strength, and cardiovascular parameters among patients who were trained based on their PFVP. Guided training utilizing heart rate variability (HRV) is also garnering increasing interest as a means to optimize training load and promote recovery

Full description

Our study aims to evaluate the application of HRV in regulating training load based on fatigue levels in cardiac rehabilitation patients utilizing the PFVP framework.

Enrollment: 110 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >18
• Acute Coronary Syndrome treated in the last 6 months
• Medical revascularization (angioplasty ± stenting) or surgical (coronary artery bypass)
• Initial CPETt: MPA ≥ 60w in women and ≥80w in men
• French
• Informed consent

Exclusion criteria

• Significant co-morbidities limited practice of physical activity

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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110 participants in 2 patient groups

Experimental group

Experimental group

Description:

Patient with acute coronary syndrome will be included. According to their initial strength-speed profile, coronary patients will benefit from an individualized cardiac rehabilitation program, with strength or speed training adapted to the autonomic nervous system (ANS).

Treatment:

Other: training strategy with adaptation of training strategies to the ANS

Control group

Active Comparator group

Description:

Patient with acute coronary syndrome will be included. According to their initial force-velocity profile, coronary patients will have an individualized cardiac rehabilitation program, either with a training in force or in velocity.

Treatment:

Other: training strategy (standard practice)