Cut-Off Progesterone Values Deleterious for In Vitro Fertilization and Fresh Embryo Transfer

Institut Universitari Dexeus

Status

Completed

Conditions

Fertilization in Vitro

Infertility

Progesterone

Pregnancy

Treatments

Other: Progesterone

Study type

Observational

Funder types

Other

Identifiers

NCT02323347

PROGEDEX2014

Details and patient eligibility

About

At which deleterious cut off value of progesterone on day of HCG (P-hCG) in our IVF program should fresh embryo transfer (ET) be cancelled?

Full description

There is still an ongoing debate on the effect of subtle increased P-hCG concentration on pregnancy outcome after fresh ET. No consensus on the cut-off value to define increased P-hCG seems to exist. It is accepted that high P advances endometrium, leading to asynchrony between the implanting embryo and the endometrium, and resulting in implantation failure. A freeze all embryos policy and postponement of ET in subsequent frozen-thawed cycle has been proposed.

Enrollment

1,901 patients

Sex

Female

Ages

18 to 49 years old

Volunteers

No Healthy Volunteers

Inclusion criteria