Cutaneous Diphtheria in France : Observational, Retrospective Study of Patient Characteristics (OEDIPE)

Intermunicipal Hospital Center Toulon

Status: Completed

Conditions: Corynebacterium Diphtheriae Infection

Treatments: Other: Characteristics description

Study type: Observational

Funder types: Other

Identifiers

NCT05798247

2022-CHITS-013

Details and patient eligibility

About

Toxigenic cutaneous diphtheria is a notifiable disease that is re-emerging in the world and particularly in France. A better description of the epidemiological characteristics, as well as a refinement of the clinical characteristics of patients with cutaneous diphtheria, are essential to better understand this pathology, which has important public health issues and whose diagnosis absence can have catastrophic consequences for the patient and their contacts. Microbiological data (species identification, toxigenicity or not, resistance profile...) will be transmitted by the national reference center for corynebacteria of the diphtheriae complex and then caregivers who have managed the corresponding patients with cutaneous diphtheria will be contacted.

Enrollment: 63 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Culture or PCR positive skin samples for corynebacteria diphtheria, ulcerans, pseudotuberculosis, belfantii or rouxii
• Patient living in metropolitan France

Exclusion criteria

• Patient opposition

Trial design

63 participants in 1 patient group

Patients with cutaneous diphteria

Description:

The study group consists of all the patients suffering from cutaneous diphtheria in metropolitan France and for which microbiological data were registered by the National Reference Center fo corynebacteria of the diphteriae complex between 2018 and 2022.

Treatment:

Other: Characteristics description