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CWT Versus AT on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy.

Cairo University (CU) logo

Cairo University (CU)

Status

Completed

Conditions

Ischemic Cardiomyopathy

Treatments

Diagnostic Test: Circuit weight versus aerobic training

Study type

Interventional

Funder types

Other

Identifiers

NCT05674955
Cw versus AT in cardiomyopathy

Details and patient eligibility

About

To compare between the effect of circuit weight and aerobic training on selected cardiovascular indices and functional capacity in patients with ischemic cardiomyopathy.

Full description

Ischemic cardiomyopathy (ICM) is a term that refers to the heart's decreased ability to pump blood properly due to myocardial damage brought upon by ischemia. Ischemic cardiomyopathy has a spectrum of clinical changes which eventually leads to congestive heart failure (CHF). Initially, there is a reversible loss of cardiac contractile function because of decreased oxygen supply to the heart muscle; however, when there is ischemia for a prolonged period, there is irreversible cardiac muscle damage resulting in cardiac remodeling. Remodeling is primarily achieved by myocardial fibrosis which results in decreased cardiac function, arrhythmia, and possible cardiac conduction system impairment. In ischemic cardiomyopathy, there is a significant impairment of the left ventricular systolic function, with a left ventricular ejection fraction (LVEF) less than 40% (Bhandari et al., 2021).

Enrollment

60 patients

Sex

Male

Ages

45 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Sixty male patients with ischemic cardiomyopathy as a result of a recent acute myocardial infarction event (≤2 months) with 40%<LVEF<50%.
  • They are functionally classified as class II according to New York Heart Association (NYHA).
  • Their age will be ranged from 45 to 55 years old.
  • Their BMI will be ranged from 25 to 29.9 kg/m².
  • They will have good mentality.

Exclusion criteria

  • Recurrent coronary heart disease.
  • Severe valvular diseases.
  • Underlying pulmonary disease (aspiration pneumonia, chronic obstructive pulmonary disease, pneumothorax, etc.).
  • Inability to ambulate owing to physical problems (paresis induced by cerebral stroke, spinal cord injury, amputation, severe pain, dyspnea, etc.).
  • muskloskletal problems (e.g. severe osteoarthritis or ankylosing spondylitis).
  • Impaired cognitive function (vascular dementia, Alzheimer's dementia, other psychological disease, etc.)

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

60 participants in 3 patient groups

Circuit weight group
Experimental group
Treatment:
Diagnostic Test: Circuit weight versus aerobic training
Aerobic group
Experimental group
Treatment:
Diagnostic Test: Circuit weight versus aerobic training
Control Group
Experimental group
Treatment:
Diagnostic Test: Circuit weight versus aerobic training

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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