Cyanoacrylate Versus Sutures for Free Gingival Graft Stabilization

Yeditepe University

Status: Completed

Conditions: Mucogingival Defects; Gingival Recession; Insufficient Keratinized Tissue

Treatments: Procedure: Free Gingival Graft Stabilization With Sutures; Procedure: Free Gingival Graft Stabilization With Butyl-Cyanoacrylate

Study type: Interventional

Funder types: Other

Identifiers

NCT07359300

YEDITEPE-FGG-2019-01

Details and patient eligibility

About

This randomized controlled clinical trial evaluated the effectiveness of butyl-cyanoacrylate tissue adhesive compared with conventional sutures for stabilization of free gingival grafts. Twenty-four patients with insufficient keratinized tissue were randomly assigned to either cyanoacrylate or suture stabilization following free gingival graft surgery. Clinical parameters, graft dimensional changes, patient-reported postoperative discomfort, and operative time were assessed over a 6-month follow-up period.

Enrollment: 24 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults aged 18 years or older
• Presence of ≤1 mm of keratinized tissue and/or Miller Class I gingival recession ≤2 mm affecting one to four mandibular anterior teeth
• Vital teeth in the surgical area
• Good oral hygiene following initial periodontal therapy (full-mouth plaque score and full-mouth bleeding score ≤20%)
• Ability to understand the study procedures and provide written informed consent

Exclusion criteria

• Current smokers
• Pregnancy or lactation
• Use of systemic antibiotics within the previous 6 months
• History of periodontal surgery in the study area
• Ongoing orthodontic treatment
• Systemic conditions that could affect periodontal healing

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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24 participants in 2 patient groups

Cyanoacrylate Stabilization Group

Experimental group

Description:

Free gingival grafts were stabilized using butyl-cyanoacrylate tissue adhesive following standard free gingival graft surgery.

Treatment:

Procedure: Free Gingival Graft Stabilization With Butyl-Cyanoacrylate

Suture Stabilization Group

Active Comparator group

Description:

Free gingival grafts were stabilized using non-resorbable polypropylene sutures following standard free gingival graft surgery.

Treatment:

Procedure: Free Gingival Graft Stabilization With Sutures