CyberCycling to Reduce Therapeutic Side Effects and Improve Quality of Life in AYA Cancers

Case Comprehensive Cancer Center (Case CCC)

Status: Completed

Conditions: Adolescent and Young Adult Cancers

Treatments: Behavioral: Stretching; Behavioral: Resistance Bands; Behavioral: CyberCycling

Study type: Interventional

Funder types: Other

Identifiers

NCT02916472

CASE4Z16

Details and patient eligibility

About

Only a few clinical trials evaluating the potential benefits of exercise have been conducted in adolescents and young adults (AYA) with cancer and, no prior studies have evaluated the potential effects of 'cybercycling' (exergaming on a stationary bike) in AYA cancer survivors. Therefore, the study aims to conduct a pilot trial to determine feasibility (adherence, user acceptance) and to explore potential effects of a 'cybercycling' exercise program on fitness, body composition, quality of life, sleep and cognition.

Full description

Objectives Specific Aim 1: To evaluate the feasibility (adherence; user acceptance: exercise tolerance, enjoyment and motivation) of performing an adaptive, moderate intensity, aerobic exercise program on a 'cybercycle' compared to control (stretching/resistance bands) in adolescent and young adults (AYA) with cancer.

(Exploratory) Aim 2: To explore the effects of an adaptive, moderate intensity aerobic exercise program using a 'cybercycle' compared to control (stretching/resistance bands) on changes in fitness, body composition, quality of life (QoL), fatigue, sleep and cognition.

Study Design/Overview:

This study is a randomized trial in 20 adolescent and young adult (AYA) cancer survivors (15-30 years old) which will comparing two intervention arms: 1) aerobic exercise on a 'cybercycle' (stationary cycling with exergaming/videogaming); and, 2) a stretching/resistance band 'control' condition.

Enrollment: 9 patients

Sex: All

Ages: 15 to 30 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• histologically confirmed cancer
• completed primary treatment
• approved to be contacted by the treating oncologist/nurse practitioner
• meet screening criteria

Exclusion criteria

• patients unable to provide informed consent
• patients not available for follow-up testing
• patients with any pre-existing medical conditions that would be a contraindication to exercise.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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9 participants in 2 patient groups

CyberCycling - Aerobic Exercise

Experimental group

Description:

30-60 mins/week, 3 days/week supervised stationary cycling with exergaming/videogaming for 12 weeks

Treatment:

Behavioral: CyberCycling

Control Stretching - Resistance Bands

Active Comparator group

Description:

2 days/week at home for 12 weeks

Treatment:

Behavioral: Resistance Bands

Behavioral: Stretching