Cyclophotocoagulation in Glaucoma

L

Laval University

Status

Completed

Conditions

Glaucoma

Treatments

Procedure: Cyclophotocoagulation protocol
Procedure: Conventional cyclophotocoagulation
Procedure: Modified cyclophotocoagulation

Study type

Interventional

Funder types

Other

Identifiers

NCT02875158
2015-2212

Details and patient eligibility

About

Transscleral cyclophotocoagulation of the ciliary body is an effective technique to reduce intraocular pressure in case of glaucoma. Due to concerns over complications, the main indications for this second-line treatment are refractory glaucoma medication / surgery and low visual prognosis. The 2000 milliwatts (mW) for 2 seconds settings are used by the majority of researchers and clinicians according to the published literature. Some have proposed using 1250 mW for 4 seconds to improve the use of this medical procedure. The aim of this study is to determine how different parameters affect the efficacy of the treatment. This is a prospective double-blinded randomized controlled trial comparing two groups, the experimental group using 1250 mW for 4 seconds and the control group using 2000 mW for 2 seconds.

Enrollment

44 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients with poorly controlled high pressure glaucoma
  • Cyclophotocoagulation necessary to prevent visual loss
  • Cyclophotocoagulation necessary to prevent or to reduce ocular discomfort

Exclusion criteria

  • Patient has already undergone a cyclophotocoagulation or cryotherapy treatment in the same eye for glaucoma
  • Patients receiving concomitant treatment the same day as the intervention
  • Patient not able to follow the prescribed post-operative treatment

Trial design

44 participants in 2 patient groups

Diode laser using conventional settings
Active Comparator group
Description:
The cyclophotocoagulation protocol is used with the conventional cyclophotocoagulation settings of 2000 mW for 2 seconds.
Treatment:
Procedure: Conventional cyclophotocoagulation
Procedure: Cyclophotocoagulation protocol
Diode laser using modified settings
Experimental group
Description:
The cyclophotocoagulation protocol is used with the modified cyclophotocoagulation settings of 1250 mW for 4 seconds.
Treatment:
Procedure: Modified cyclophotocoagulation
Procedure: Cyclophotocoagulation protocol

Trial contacts and locations

0

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Central trial contact

Andrew Toren, Doctor

Data sourced from clinicaltrials.gov

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