ClinicalTrials.Veeva

Menu

Cytokine Profile of Conjunctivitis, Performed Through Tears Analysis Among Patients Treated With Dupilumab (CYCLADDE)

C

Centre Hospitalier Universitaire de Besancon

Status

Unknown

Conditions

Atopic Dermatitis
Conjunctival Diseases
Side Effect

Treatments

Other: Tears sampling
Other: Lashes sampling

Study type

Interventional

Funder types

Other

Identifiers

NCT04066998
P/2019/424

Details and patient eligibility

About

This study aims to assess the cytokine profile of tears in patients suffering from conjunctivitis versus patients without ocular involvement, when treated with Dupilumab

Enrollment

15 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients with severe atopic dermatitis resistant to main immunosuppressive drugs
  • treated with Dupilumab
  • with or without conjunctivitis
  • postmenopausal women (since minimum 24 months), surgically sterilized women or women on contraception

Exclusion criteria

  • pregnant or breastfeeding women

Trial design

Primary purpose

Other

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

15 participants in 2 patient groups

Conjunctivitis
Experimental group
Description:
Patients treated with Dupilumab with conjunctivitis
Treatment:
Other: Lashes sampling
Other: Tears sampling
No conjunctivitis
Other group
Description:
Patients treated with Dupilumab and showing no signs of ocular involvement
Treatment:
Other: Lashes sampling
Other: Tears sampling

Trial contacts and locations

0

Loading...

Central trial contact

Louise VUILLEMEY, Int

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems