Cytokine Profile of the Uterine Secretome After Therapeutic Endometrial Scratching

University of Aarhus

Status: Completed

Conditions: Infertility, Female

Treatments: Other: Pipelle de Cornier

Study type: Interventional

Funder types: Other

Identifiers

NCT03042364

Miacol-2017-3H

Details and patient eligibility

About

This study investigates the impact of endometrial scratching on endometrial secretion, when correlated to pregnancy.

Enrollment: 150 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• IVF or ICSI patients with ≥1 previous implantation failure, despite transfer of a top quality embryo or blastocyst.
• Antagonist treatment
• FSH: 2-12 IU/L
• BMI: 18-32
• Regular menstrual cycle
• Written consent

Exclusion criteria

• Suspected intrauterine abnormalities Planned use of specialized media or AHA

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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150 participants in 2 patient groups

No intervention

No Intervention group

Description:

Standard treatment

Intervention

Experimental group

Description:

Endometrial scratching before standard treatment

Treatment:

Other: Pipelle de Cornier