Cytokines of Patients With Transversus Abdominis Plane Block After Laparoscopic Colonic Surgery

China Medical University, China

Status and phase: Completed; Phase 4

Conditions: Laparoscopic Colonic Surgery

Treatments: Drug: transversus abdominis plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT02219542

20140804

Details and patient eligibility

About

The investigators designed a study to determine whether with combined general-transversus abdominis plane block anesthesia or standard general anaesthetic would provide same level of cytokines in patients undergoing Laparoscopic Colonic Surgery.

Full description

The investigators designed a study to determine whether combined general-transversus abdominis plane block anesthesia or standard general anaesthetic would provide same level of cytokine in patients undergoing Laparoscopic Colonic Surgery.

Enrollment: 80 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• •Participants were deemed eligible if they were candidates for spinal anesthesia undergoing Laparoscopic Colonic Surgery

Exclusion criteria

• •Existing cognitive impairment as evidenced by Mini-Mental State Examination scores below 24 (of the 30 possible points)

  • A history of neurological and psychiatric diseases including stroke, and psychosis
  • Severe visual or hearing impairment
  • Unwillingness to comply with the protocol or procedures

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups, including a placebo group

a standard general anesthesia

Placebo Comparator group

Description:

a standard general anesthesia and with transversus abdominis plane block 20 ml 0.9% sodium chloride

Treatment:

Drug: transversus abdominis plane block

Drug: transversus abdominis plane block

transversus abdominis plane block

Experimental group

Description:

a standard general anesthesia with transversus abdominis plane block 20 mL 0.25% ropivacaine

Treatment:

Drug: transversus abdominis plane block

Drug: transversus abdominis plane block