Cytomegalovirus (CMV) Transmission by Frozen Breast Milk in Preterms

Johann Wolfgang Goethe University Hospital

Status: Suspended

Conditions: Cytomegalovirus

Study type: Observational

Funder types: Other

Identifiers

NCT00668798

CMV/MM0105/FFM

Details and patient eligibility

About

Cytomegalovirus infection threatens preterm infant. We investigated, whether thawed breast milk is a mode of transmission

Full description

Preterm infants are at risk of symptomatic human cytomegalovirus infections transmitted by breast milk. This study evaluates incidence, timing, and clinical rlevance of acquired human CMV infections in preterm infants younger than 32 weeks of gestational age receiving maternal thawed frozen breast milk until 33 completed weeks of gestational age.

Enrollment: 58 patients

Sex: All

Ages: 24 to 31 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• preterm infants of less than 32 weeks of gestation

Exclusion criteria

• preterm infant of 32 weeks of gestational age or older, feeding with solely formula milk
• ourborn infants
• retroviral infection
• CMV status of mother unclear
• informed consent missing

Trial design

58 participants in 2 patient groups

A

Description:

mother CMV positive

B

Description:

mother CMV negative