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Cytomegalovirus Reactivation in Cancer Patients Receiving Chemotherapy

M

Mackay Memorial Hospital

Status

Completed

Conditions

Cytomegalovirus
Cancer

Study type

Observational

Funder types

Other

Identifiers

NCT00366717
MMH-I-S-144

Details and patient eligibility

About

Cytomegalovirus (CMV) infects most of the world population. This study is to understand if chemotherapy will increase the chance of reactivating CMV. The results may help us in determining when treatment is needed and perhaps Why is it needed.

Full description

Despite CMV reactivation has been clearly described in patients underwent transplantation, this phenomenon has not been studied in patients undergoing chemotherapy. Our purpose is to understand if CMV number increases in monocytic leukocytes during chemotherapy and how is the host response to that changes.

Virus load will be studied by quantitative PCR, host response will be studied by measuring patient's anti-CMV IgG, CMV-associated symptoms, serum IFN-r and TNF-a.

Sex

All

Ages

20+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • clinical diagnosis of any cancer
  • chemotherapy is needed for more than 6 months
  • age>20 years old

Exclusion criteria

  • those who do not agree to participate

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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