Cytosorb Therapy in Cardiac Surgery

University Hospital Basel

Status

Completed

Conditions

Endocarditis

Cardiopulmonary Surgery

Peri-operative Cytokines Levels

Treatments

Device: CytoSorb haemoadsorption (HA) device

Study type

Observational

Funder types

Other

Identifiers

NCT04309591

2019-01740 ch19Santer;

Details and patient eligibility

About

Cardiopulmonary surgery is associated with inflammatory responses that can lead to systemic inflammatory responses (SIRS), organ dysfunction (MOD) and death especially in patients with endocarditis. Cytokine removal might therefore improve outcomes of patients undergoing cardiac surgery. CytoSorb is a device designed to remove cytokine (IL-6, IL-10, TNFalpha) from the blood to reduce immune reactions. This trial investigates the use of CytoSorb during cardiac surgery in patients with endocarditis at the University Hospital Basel.

Enrollment

249 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria