D-dimer Prognostic Marker of Cerebral Infarction After Revascularization Procedure (D-Dimer)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Cerebral Infarction; Cerebral Infarction Recovery

Treatments: Biological: blood sample

Study type: Observational

Funder types: Other

Identifiers

NCT04938479

PI2020_843_0159

Details and patient eligibility

About

Cerebral infarction is the leading cause of acquired disability in adults. Absence of biological marker used in current practice and identified as a prognostic factor for recovery. D-dimers are degradation products of stabilized fibrin translating an activation of coagulation whatever the cause. Studies have shown that increased D-dimer levels in patients with MI is associated with a higher mortality rate, the link with post-intervention non-revascularization has been demonstrate.

The purpose of this project is to search for a correlation between the level of D-dimer and the degree of recovery evaluated by the NIHSS score

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18 to 65
• Cerebral infarctions undergoing a revascularization procedure by thrombolysis and / or thrombectomy, at the Amiens University Hospital between January 2015 and December 2020.
• Patients having benefited from a D-dimer assay (during their stay)

Exclusion criteria