D Vitamin and Alveolar Macrophages in Idiopathic Pulmonal Fibrosis

University of Aarhus

Status: Enrolling

Conditions: Idiopathic Pulmonary Fibrosis (IPF)

Study type: Observational

Funder types: Other

Identifiers

NCT06909409

1-10-72-166-23

Details and patient eligibility

About

The goal of this observational study is to gain deeper insights into human macrophages and vitamin D, and their interplay, within Idiopathic Pulmonary Fibrosis (IPF).

The overall questions, it aims to answer, are the following:

Do IPF patients suffer from systemic and local (pulmonary) insufficient levels of vitamin D? Do IPF patients suffer from pro-fibrotic and pro-inflammatory pulmonary macrophages?

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• A clinical diagnosis of IPF, non-IPF ILD or lung cancer
• A signed informed consent

Exclusion criteria

• Do not speak Danish/Do not understand Danish

Trial design

120 participants in 3 patient groups

Patients with IPF

Patients with non-IPF interstitial lung disease (ILD)

Patients with lung cancer