Daily Activities Are Sufficient to Induce Dynamic Pulmonary Hyperinflation and Dyspnea in Chronic Obstructive Pulmonary Disease Patients

Federal University of São Paulo

Status: Completed

Conditions: Activities of Daily Livin.; Dynamic Lung Hyperinflation; COPD Patients

Treatments: Other: Hyperinflation and ADL

Study type: Observational

Funder types: Other

Identifiers

NCT01475812

0353/03

Details and patient eligibility

About

Introduction: Chronic obstructive pulmonary disease is a condition characterized by airflow limitation usually progressive and associated with inflammatory response of lung noxious particles. During a physical activity chronic obstructive pulmonary disease patients may develop dynamic pulmonary hyperinflation, increased dyspnea perception and decreased activity performance. The investigators hypothesize that some specific activities of daily living induce dynamic pulmonary hyperinflation in COPD patients. Objective: To measure dynamic lung hyperinflation and its influence in dyspnea perception in moderate and severe chronic obstructive pulmonary disease patients after activities of daily living. Methods: The investigators measured inspiratory capacity, dyspnea sensation, peripheral oxygen saturation, heart rate and respiratory rate in 19 chronic obstructive pulmonary disease (COPD) patients. These measurements were taken at rest and after daily living activities (such as going up and down a set of stairs, going up and down a ramp and sweeping and mopping a room).

Enrollment: 19 patients

Sex: All

Ages: 50 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• COPD patients diagnosed with moderate to very severe airway obstruction according to GOLD classification (9)
• clinical stability with no clinical exacerbation during the previous 30 days prior to the beginning of the study and to sign an informed consent form

Exclusion criteria

• Inability to perform the slow vital capacity maneuver
• excessive perceived dyspnea during the test
• arterial oxyhemoglobin saturation (SpO2) lower than 80% during activities and/or need of oxygen supplementation

Trial design

19 participants in 1 patient group

COPD hyperinflation

Treatment:

Other: Hyperinflation and ADL