Daily Activity After Corticosteroids Injection Among Knee Osteoarthritis Patients

Laval University

Status and phase: Completed; Phase 4

Conditions: Knee Osteoarthritis

Treatments: Drug: Corticosteroids injection

Study type: Interventional

Funder types: Other

Identifiers

NCT02049879

INF-2010

Details and patient eligibility

About

The objective of this study was to objectively measure daily physical activity and spatiotemporal gait pattern, as well as improvements in self reported symptoms and quality of life, before and six weeks after an intra-articular corticosteroids injection in patients suffering from knee osteoarthritis. Fourteen patients with unilateral knee osteoarthritis were recruited. The intra-articular corticosteroid injection was given at the end of the second week. Physical activity was objectively measured by an accelerometer worn by the participants for eight weeks. In addition, the Western Ontario and McMaster Universities Arthritis Index (WOMAC), the Medical Outcome Study Short Form-36 (MOS-SF36) and gait trials were completed every two weeks to assess symptoms, quality of life and spatiotemporal parameters of gait.

Enrollment: 14 patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 50 years old or more
• Medial knee osteoarthritis (Kellgren & Lawrence Grade I to III)

Exclusion criteria

• Intra-articular injection during the last six months
• Isolated femoro-patellar arthritis
• Rheumatoid arthritis
• Knee instability
• Spinal stenosis
• Lower limb fracture over the last year
• Lower limb surgery in the last three months

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

14 participants in 1 patient group

Injection

Experimental group

Description:

Corticosteroids injection

Treatment:

Drug: Corticosteroids injection