Daily Protein Intake Distribution and MPS (ARCIII)

Nestlé

Status: Completed

Conditions: Overweight

Treatments: Other: whey protein; Other: placebo

Study type: Interventional

Funder types: Industry

Identifiers

NCT02315014

12.12.NRC

Details and patient eligibility

About

To determine whether a balanced total daily dietary protein distribution supplemented with whey protein during a weight-loss intervention will result in increased muscle protein synthesis

Enrollment: 20 patients

Sex: Male

Ages: 60 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Overweight/obese (BMI 27-40 kg/m2)
• Non-smokers
• Non-diabetic
• No history of hyperlipidemia
• Not taking medications thought to interfere with study
• Considered generally healthy

Exclusion criteria

• Efforts to lose weight in previous 16 weeks
• Hyperlipidemia
• Blood pressure ≥ 140/90 mmHg
• Smoking
• Heart and other organ disease
• Type 2 diabetes
• Gastrointestinal disease
• Orthopedic injury interfering with exercise
• Use of certain medications (HRT, antihypertensives, diuretics, antiarythmia medications, antiresorptive agents, anabolic agents, hypoglycemic agents, and statins known to affect muscle i.e. Simvastatin and Zocor)

Trial design

20 participants in 2 patient groups, including a placebo group

whey protein

Experimental group

Description:

whey protein micelles

Treatment:

Other: whey protein

placebo

Placebo Comparator group

Description:

calorie-free placebo

Treatment:

Other: placebo