Daily Undulating Periodization Methods With Parkinson's Disease

University of Miami

Status: Completed

Conditions: Weight-Lifting Exercise Program; Parkinson Disease

Treatments: Other: Simple Periodized Training; Other: Periodized training with motor practice

Study type: Interventional

Funder types: Other

Identifiers

NCT03867877

20181119

Details and patient eligibility

About

Compare periodized (cyclic) resistance training with and without motor training specific to activities of daily living.

Full description

This study will look at how well two different daily undulating training programs (hypertrophy-strength-power training, versus strength-power-functional training) improve participants' physical functions. All testing procedures will take place at the Max Orovitz Laboratory on the Coral Gables campus. This study will involve a 1-week baseline testing phase, a 2-week familiarization phase, a 9-week intervention phase, and a 1-week post-testing window where subjects must report to the lab for 2 sessions.

Enrollment: 40 patients

Sex: All

Ages: 40 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hoehn & Yahr Classification of Disability, stage 1-3
• can ambulate with or without an assistive device for at least 50 feet
• able to get up and down from the floor with minimal assistance
• has a score of 24 or above on the Folstein Mini-Mental State Exam

Exclusion criteria

• Greater than Stage 3 on the Hoehn & Yahr Classification of Disability
• decline in immune function such as pneumonia or systemic infection
• progressive degenerative disease besides PD
• spinal fusion or other orthopedic surgery in the past six months
• mental disease/psychosis such as dementia
• greater than minimal assistance required for gait and transfers
• inability to make regular time commitments to the scheduled training sessions
• participation in resistance training on a regular basis within the past six months
• inability to provide consent
• pregnancy
• a prisoner

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Periodized Training with Motor Practice

Experimental group

Description:

Strength training will use 75-80% of the subject's maximum for the specific exercise and contractions will occur at 2s concentric and 3s eccentric for the strength day. 30-80% of subjects' maximal strength for the power day with high-speed concentric and 2 second eccentric contractions, and exercises that simulate activities of daily living for the motor practice day. All resistance-training will be performed on Keiser air-driven machines. Subjects will perform 10 exercises targeting all major muscle groups. The training will last for 12 consecutive weeks, for a total of 36 visits. Each visit will be approximately 60 minutes long and will consist of 5 minutes warm-up, 50 minutes of training and five minutes of cool-down.

Treatment:

Other: Periodized training with motor practice

Simple Periodized Training

Experimental group

Description:

Strength training will use 75-80% of the subject's maximum for the specific exercise and contractions will occur at 2 second concentric and 3 second eccentric for the strength day. 30-80% of subjects' maximal strength for the power day, with high speed concentric and 2 second eccentric contractions, and 60-75% of subjects' maximum strength for the hypertrophy day. All resistance-training will be performed on Keiser air-driven machines. Subjects will perform 10 exercises targeting all major muscle groups. The training will last for 12 consecutive weeks, for a total of 36 visits. Each visit will be approximately 60 minutes long and will consist of 5 minutes warm-up, 50 minutes of training and five minutes of cool-down

Treatment:

Other: Simple Periodized Training