Dairy Based Probiotic Intervention and Cognitive, Emotional, and Inflammatory Outcomes

University of Idaho

Status: Completed

Conditions: Inflammation; Cognitive Change; Cognitive Decline; Emotions

Treatments: Other: Yogurt

Study type: Interventional

Funder types: Other

Identifiers

NCT04643080

18-203

Details and patient eligibility

About

The purpose of this study was to determine the effect of dairy-based probiotics on cognitive function, emotional wellbeing, and inflammation. Subjects were assigned to either consume 6 oz of yogurt/day or abstain from consuming yogurt and other probiotic-containing foods for 12 weeks. Subjects completed baseline testing and 12-week follow-up testing consisting of a laboratory blood draw to assess inflammatory biomarkers, and a computerized assessment to evaluate cognitive and emotional wellbeing measures.

Enrollment: 47 patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ability to participate in a 12-week study
• at least 50 years of age
• not currently taking a probiotic dietary supplement
• willing to refrain from consuming probiotic dietary supplements or fermented foods for 12-weeks
• willing to have blood drawn twice
• willing to consume yogurt daily for 12 weeks

Exclusion criteria

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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47 participants in 2 patient groups

Control

No Intervention group

Description:

Subjects were asked to avoid consuming fermented foods for 12 weeks.

Yogurt

Experimental group

Description:

Subjects were asked to consume 6 oz. of yogurt daily for 12 weeks.

Treatment:

Other: Yogurt