Dairy Intake and Brain Health in Aging

University of Kansas

Status

Completed

Conditions

Aged Healthy Volunteer

Study type

Observational

Funder types

Other

Identifiers

12884

Details and patient eligibility

About

The purpose of this study is to learn if dairy food consumption may help brain health in aging by protecting nerve cells from oxidative damage.

Enrollment

60 estimated patients

Sex

All

Ages

60 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Males and females between 60-85 years of age.
Good general health with no concomitant diseases, which would be expected to interfere with the study
BMI range 20-35 kg/m2

Exclusion criteria

Presence of any central neurological disease with the potential to impair cognition(e.g., brain tumor, stroke, epilepsy, motor neuron disease, multiple sclerosis, Alzheimer disease, Parkinson's disease) or prior major head trauma with loss of consciousness
Presence of an active unstable and life-threatening systemic illness (e.g., cancer)
Presence of major psychiatric disorder within the past 3 years including depression, anxiety, and alcohol (over 3 drinks per day or total of 18 per week) or drug abuse (DSM-IV criteria; Geriatric Depression Score>6)
Presence of diabetes mellitus (defined as a clinical diagnosis or use of an anti-diabetic agent) and metabolic syndrome
Use of psychoactive and investigational medications
Subjects with MRI contraindications such as pacemaker, aneurysm clips, artificial heart valves, metal fragments, foreign objects or claustrophobia. All subjects subjects will receive a structural MRI as part of this study. Individuals with evidence of infection, infarction, neoplasm or other lesions will be excluded. Individuals found to have abnormalities in their structural MRI will be referred to their primary physician for further evaluation and management.
Pregnancy
Special diet regimens such as lactose free or vegan