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Dairy Proteins and Postprandial Appetite Regulation and Energy Expenditure (MAES)

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University of Copenhagen

Status

Completed

Conditions

Obesity

Treatments

Dietary Supplement: dairy proteins

Study type

Interventional

Funder types

Other
Industry

Identifiers

Details and patient eligibility

About

The aim of this study is to examine the effect of dairy proteins (whey and casein) on postprandial appetite regulation and energy expenditure.

Full description

Several studies have shown that a high protein intake is associated with a increased loss of body weight and body fat as compared to a diet with a normal or low protein content. The effect seems to be due to a higher diet induced thermogenesis and increase satiety.

Milk has a high content of proteins. It contains two very different types of protein: whey and casein. Whey is a soluble protein whereas casein clots into the stomach, which delays its gastric emptying and thus probably results in a slower release of amino acids. It is therefore very likely that the two types of protein affect the thermogenesis and appetite regulation differently.

The aim of the present study is to examine the effect of dairy proteins (whey and casein) on postprandial energy expenditure, substrate oxidation and appetite regulation.

The study will have a cross-over design including four meals each including a test drink (milk, casein drink, whey drink or water).

Enrollment

22 patients

Sex

Male

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • healthy males
  • body mass index (BMI) 25-30 kg/m2
  • 18-50 years
  • weight stable

Exclusion criteria

  • smoker
  • regular use of medicine
  • elitist athletes
  • participation in other intervention studies

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

22 participants in 4 patient groups

milk
Experimental group
Description:
skim milk
Treatment:
Dietary Supplement: dairy proteins
casein drink
Experimental group
Treatment:
Dietary Supplement: dairy proteins
whey drink
Experimental group
Treatment:
Dietary Supplement: dairy proteins
water
Sham Comparator group
Treatment:
Dietary Supplement: dairy proteins

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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