Danish Breast Cancer Group Internal Mammary Node Study (DBCG IMN)

Danish Breast Cancer Cooperative Group (DBCG)

Status: Active, not recruiting

Conditions: Breast Cancer

Treatments: Radiation: Internal mammary node irradiation

Study type: Interventional

Funder types: Other

Identifiers

NCT06549920

DBCG IMN protocol

Details and patient eligibility

About

The DBCG IMN study is a nationwide prospective population-based cohort study allocating node-positive breast cancer patients with right-sided tumors to internal mammary node irradiation (IMNI) and patients with left-sided tumors to no IMNI.

Enrollment: 7,630 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with macrometastatic node-positive breast cancer treated with loco-regional radiotherapy.

Exclusion criteria

• Prior malignancies, bilateral breast cancer, neoadjuvant systemic therapy, recurrence before radiotherapy, and non-standard radiotherapy.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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7,630 participants in 2 patient groups

Internal mammary node irradiation

Experimental group

Description:

Patients with right-sided breast cancer tumors were allocated to internal mammary node irradiation.

Treatment:

Radiation: Internal mammary node irradiation

No internal mammary node irradiation

No Intervention group

Description:

Patients with left-sided breast cancer tumors were allocated to no internal mammary node irradiation.