Daptomycin Concentration in Drainage Fluid and Blood Samples of ICU Patients

University Hospital Tuebingen

Status: Completed

Conditions: Heart Assist Device

Treatments: Drug: Daptomycin

Study type: Observational

Funder types: Other

Identifiers

NCT03004066

Dapto

Details and patient eligibility

About

10 patients with chronic heart failure receiving daptomycin therapy after implantation of a left ventricular heart assist system. Measurement of daptomycin levels in drainage fluids (mediastinal and pleural drainage systems) and in blood samples.

Enrollment: 9 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• written consent
• heart assist device implantation
• wound drainage
• daptomycin therapy

Exclusion criteria

• pregnancy
• no written consent possible
• absence of wound drainage
• allergy to study medication
• acute rhabdomyolysis