Dark Halo and MNV: a Study Between ICGA and OCTA

Federico II University

Status: Completed

Conditions: Macular Neovascularisation

Treatments: Diagnostic Test: Optical Coherence Tomography Angiography (OCTA) and indocyanine green angiography (ICGA)

Study type: Observational

Funder types: Other

Identifiers

NCT05108285

9009/21

Details and patient eligibility

About

The aim of study is to compare the evaluation of dark halo area of macular neovascularization (MNV) between indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCTA) in order to identify OCTA as effective and useful biomarker in MNV

Full description

Dark halo is defined as a dark perilesional of flow decrease due to an area of reduced choroidal flow adjacent to the macular neovascularization (MNV).

The detection of MNV vascular details was only possible through invasive dye injection, such as fluorescein angiography (FA) or indocyanine green angiography (ICGA).

Optical coherence tomography angiography (OCTA) is a recent imaging technique that is able to detect the perfusion and non-perfusion areas carefully.

The aim of study is to compare the evaluation of dark halo area of MNV between ICGA and OCTA

Enrollment: 50 patients

Sex: All

Ages: 55 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age older than 55 years
• diagnosis of macular neovascularization
• absence of previous treatment with anti-Vegf injections
• absence of other retinal vascular diseases

Exclusion criteria

• age younger than 55 years
• absence diagnosis of macular neovascularization
• presence of previous treatment with anti-Vegf injections
• presence of other retinal vascular diseases

Trial design

50 participants in 1 patient group

MNV group

Description:

Eyes affected by MNV. The dark halo of MNV was evaluated by OCTA and ICGA

Treatment:

Diagnostic Test: Optical Coherence Tomography Angiography (OCTA) and indocyanine green angiography (ICGA)