Database of Monochorionic Pregnancies

University of Miami

Status: Enrolling

Conditions: Monochorial Monoamniotic Placenta; Twin; Complicating Pregnancy; Monochorionic Diamniotic Placenta; Twin Reversal Arterial Perfusion Syndrome; Twin to Twin Transfusion Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT05543499

20210709

Details and patient eligibility

About

The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.

Enrollment: 1,200 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• The study population will consist of MC pregnancies (maternal, fetal, and neonatal data) that have undergone evaluation and/or treatment for complications attributable to monochorionic twin pregnancy at the University of Miami.
• Maternal age 18 years and older.

Exclusion criteria

• Participation declined or consent not granted in prospective arm
• Loss to follow-up

Trial design

1,200 participants in 1 patient group

Monochorionic Pregnancy Group

Description:

Participants with complicated monochorionic pregnancies (MC) will be followed prospectively beginning at the time of the mother's evaluation for a complication related to monochorionic (MC) multiple pregnancies through delivery of the child and follow-up of the child to 12 months of life.