Daytime Profile of Salivary Progesterone

Peter Humaidan

Status: Completed

Conditions: Infertility, Female

Treatments: Diagnostic Test: Progesterone analysis in saliva

Study type: Interventional

Funder types: Other

Identifiers

NCT03725904

Saliva1

Details and patient eligibility

About

The aim of this study is to perform a 12-hour profile of free saliva progesterone during the luteal phase after fresh and frozen embryo transfer. If progesterone levels in saliva samples show a constant level during daytime, this non-invasive measurement can be used in future ART patients with insufficient progesterone levels who might benefit from additional exogenous progesterone supplementation.

Enrollment: 20 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-45 years
• One or two good quality embryos for transfer on day 5.
• BMI >18,5 <30 kg/m²

Exclusion criteria

• No good quality embryos for transfer
• Uterine abnormalities
• One ovary
• Oocyte donation

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

IVF/FET

Experimental group

Treatment:

Diagnostic Test: Progesterone analysis in saliva