De-implementation of Outdated Colonoscopy Surveillance Interval Recommendations Among Patients With Low-risk Adenomas (DESIRE)

Kaiser Permanente

Status: Completed

Conditions: Polyp of Colon

Treatments: Behavioral: Outreach

Study type: Interventional

Funder types: Other

Identifiers

NCT05389397

1789503-1

Details and patient eligibility

About

The purpose of this study is to compare the effectiveness of three standard of care outreach approaches (i.e., mailed letter, secure message, and telephone call) on patient adoption of the new 10-year colonoscopy surveillance interval recommendation for a random sample of health plan members who have a now-outdated 5-year surveillance interval due to a finding of 1-2 small adenomas at their prior colonoscopy. The primary study endpoint is the proportion of patients in each outreach arm who adopt the new 10-year colonoscopy surveillance interval.

Enrollment: 604 patients

Sex: All

Ages: 54 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Kaiser Permanente Northern California (KPNC) membership>12 months
• Primary medical center is either KP San Rafael, KP San Francisco, KP San Leandro, or KP Walnut Creek
• 54-70 years of age at time of 5-year surveillance colonoscopy interval
• A baseline colonoscopy with a finding of 1-2 small tubular adenomas and are due for their 5-year surveillance procedure in 2022
• Average risk for CRC
• A valid mailing address, kp.org account (i.e., KPNC's secure messaging portal), and telephone number at time of study enrollment.

Exclusion criteria

• More than 12 months of membership prior to index colonoscopy, and indications that would make an individual above average risk for CRC, such as: adenoma with advanced histology on colonoscopy, adenoma >10 mm on colonoscopy, family history of CRC, prior history of colonoscopy, prior history of adenomas or colon polyp diagnoses, history of IBD, history of hereditary polyposis syndrome, 3 or more adenomas, adenoma 10 mm in size or greater, adenoma with advanced histology, and any sessile serrated polyp or traditional serrated adenoma

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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604 participants in 3 patient groups, including a placebo group

Mailed Letter

Placebo Comparator group

Treatment:

Behavioral: Outreach

Secure Message

Active Comparator group

Treatment:

Behavioral: Outreach

Telephone Outreach

Active Comparator group

Treatment:

Behavioral: Outreach