Decision-making - the Benefit of Bedside CRP Within Ambulance Care (Q-CRP)

Helsinki University Central Hospital (HUCH)

Status

Completed

Conditions

Critical Illness

Treatments

Diagnostic Test: POC

Study type

Observational

Funder types

Other

Identifiers

NCT04097210

HUS 329/13/3/02/2015

Details and patient eligibility

About

Patients with degreased (DGC) for ambiguous reasons receive low triage priority. Their death risk is triple. Tools are needed to identify the critically ill patients from this group. The triage used today is not effective. The bedside point-of-care measurements are CRP, lactate acid and suPAR (Soluble Urokinase Plasminogen Activator Receptor). Elevated values associate with the probability of critical illness and predict a risk of death.

Full description

Purpose: To improve identification and proper prioritization of patients with non-specific symptoms prehospitally, we intend to investigate whether Q-CRP, a rapid test for CRP, correlates with time-critical states in the above-mentioned patient group alone or together with CRP, lactate and suPAR. The primary endpoint is need for hospital care.

Material: Patients over 18 years who exhibit non-specific symptoms and transported to the emergency room.

Method: In patients with unspecified conditions, defined according to the inclusion template, a venous blood sample was taken prehospitally at the scene by the EMS.

Analysis: Significance tests and regression analyzes with 95% CI were used. The diagnostic accuracy of Q-CRP, lactate, suPAR and combinations thereof were compared with optimal boundary values.

Enrollment

110 patients

Sex

All

Ages

16 to 104 years old

Volunteers

No Healthy Volunteers

Inclusion criteria