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Decision Support for Heart Failure Prescribing

University of Colorado Denver (CU Denver) logo

University of Colorado Denver (CU Denver)

Status

Active, not recruiting

Conditions

Decision Support Systems, Clinical
Heart Failure

Treatments

Other: Personalized Clinical Decision Support (CDS)
Other: Traditional Clinical Decision Support (CDS)

Study type

Interventional

Funder types

Other

Identifiers

NCT06293794
22-0991

Details and patient eligibility

About

Clinical decision support (CDS) tools can 'nudge' clinicians to make the best decisions easy. Although required by "meaningful use" regulations, more than 40% of CDS lead to no change and the remaining lead to improvements that are modest at best. This is because CDS tools often ignore contextual factors and present irrelevant information. Although many tools have undergone patient-specific optimization, 'traditional CDS' are rarely clinician-specific. For example, a traditional CDS tool for beta blockers and heart failure with reduced ejection fraction (HFrEF) addresses common prescribing misconceptions by stating asthma is not a contraindication and providing a safe threshold for blood pressure. For clinicians without these misconceptions, these statements are irrelevant and distract from key information. A 'personalized CDS' would evaluate clinician past prescribing patterns to determine whether prescribing misconceptions might exist and then conditionally present information to address those misconceptions. The objective of this research is to create personalized clinician-specific CDS that overcome shortcomings of traditional CDS. The central hypothesis is a personalized CDS that minimizes irrelevant information will lead to a higher rate of prescribing guideline-directed management and therapy (GDMT) for HFrEF compared to a traditional CDS.

Enrollment

764 patients

Sex

All

Ages

18 to 89 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • The study subjects are potential users of the CDS, specifically clinicians with prescribing privileges who practice at one of the health system's (UCHealth) outpatient cardiology or primary care clinics. Because we are observing their prescribing behaviors, we are also evaluating patient characteristics which could influence their prescribing decisions.

Exclusion criteria

  • Clinicians who do not practice in cardiology or primary care clinics or do not practice within UCHealth system.

Trial design

Primary purpose

Health Services Research

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

764 participants in 2 patient groups

Traditional Clinical Decision Support (CDS)
Experimental group
Treatment:
Other: Traditional Clinical Decision Support (CDS)
Personalized Clinical Decision Support (CDS)
Experimental group
Treatment:
Other: Personalized Clinical Decision Support (CDS)

Trial contacts and locations

1

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Central trial contact

Cathryn Perreira, MA; Katy Trinkley, PharmD, PhD

Data sourced from clinicaltrials.gov

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