Decoding Chronic Pain With fMRI

University of Cambridge

Status: Completed

Conditions: Chronic Back Pain

Study type: Observational

Funder types: Other

Identifiers

NCT01766973

CE-U.NA.NFLT.EGDF

Details and patient eligibility

About

Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.

Enrollment: 76 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 18-60
• pain > 6months
• right-handed
• non-smoking
• mechanical back pain

Exclusion criteria

• significant neurological or psychiatric disease
• major systemic illness
• MRI exclusion criteria

Trial design

76 participants in 2 patient groups

Chronic back pain

Description:

Adults, \>6months duration

Control

Description:

Age and sex matched controls