Deconstructing Voice Therapy: Towards Enhanced Communication Outcomes

Emory University

Status

Enrolling

Conditions

Dysphonia

Primary Muscle Tension Dysphonia (MTD)

Treatments

Other: Hierarchical method

Other: Non Hierarchical method

Study type

Interventional

Funder types

Other

NIH

Identifiers

NCT07176988

STUDY00009121

1R01DC022026-01A1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This research study aims to evaluate the effect of treatment delivery method on voice outcomes over 12 months in people with a primary complaint of a voice problem, diagnosed with either non-phonotraumatic vocal hyperfunction, also known as primary muscle tension dysphonia (MTD) or phonotraumatic vocal hyperfunction, also known as benign vocal fold lesions (lesions).

The secondary objectives are:

To evaluate acoustic correlates of clear speech and the relationship to vocal acoustic and patient-reported voice outcomes.
To determine the association between overall dysphonia outcomes and adoption of clear speech.

Full description

About 23 million Americans-roughly 1 in 13 people-suffer from voice problems at any given time. These issues can make it hard to speak clearly, lead to throat pain or fatigue, and affect daily life, work, and emotional well-being. The two most common types of voice problems are:

Muscle tension dysphonia (MTD): when muscles in the throat are too tight during speaking.
Benign vocal fold lesions: such as nodules or swelling on the vocal cords due to overuse or strain.

The most common treatment for these conditions is behavioral voice therapy, which involves working with a speech-language pathologist (SLP) to learn new ways to use the voice. However, over a third of patients drop out, and long-term success is uncertain. One major challenge is helping patients apply what they learn in therapy to their real-life conversations-a step often saved for the end of treatment or skipped entirely.

Traditional voice therapies often follow a strict step-by-step ("hierarchical") approach. Patients start with basic sounds or exercises and only work up to everyday speech later. But this method may not be the most effective, and many people struggle to use the new techniques outside the clinic.

To solve this problem, the research team developed a new method called Conversation Training Therapy (CTT). CTT flips the traditional approach: it begins with practicing clear, intentional speech in real conversation from the first session. This helps patients immediately apply new voice skills in real-life situations, which may lead to faster, more lasting results.

Studies have shown that CTT leads to meaningful improvements in voice-related quality of life both immediately and up to three months after therapy. It is now being used in national research studies and has gained recognition as a promising, evidence-based therapy. The current research will compare CTT to traditional methods over a full year, helping to answer important questions about what makes voice therapy work-and how to help more people benefit from it long-term.

Enrollment

120 estimated patients

Sex

All

Ages

16 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Non-smoking
Diagnosis of either primary muscle tension dysphonia of the hyperadducted type or benign vocal fold lesions.
No neuro-laryngologic or age-related vocal fold changes (e.g., atrophy)
No history of voice therapy or voice surgery in the last year
No history of other serious chronic medical conditions that may affect voice (per patient report), Normal hearing (determined by pure tone audiometry), stimulable and appropriate for behavioral voice intervention as determined by a voice-specialized speech-language pathologist and laryngologist,
Willingness to attend all therapeutic interventions and follow-up sessions
Willingness to use a smartphone to record practice

Exclusion criteria

History of voice therapy or voice surgery in the last year
Serious chronic medical condition that may affect voice (per patient report)
Abnormal hearing ability (despite appropriate amplification)
Other laryngeal disorders not attributed to primary MTD and benign vocal fold lesions,
Not stimulable or inappropriate for behavioral voice intervention as determined by a voice-specialized speech-language pathologist and laryngologist
Unwillingness to attend therapeutic intervention and follow-up sessions
Unwillingness to use a smartphone to record practice
Pregnant women
Prisoners
Cognitive impairment or impaired decision-making capacity